Biochemistry & Biophysics Scientist

Biochemistry & Biophysics Scientist

Website Atavistik Bio

Position Summary

We are looking for a multitalented and self-driven individual with a strong background in biochemical and biophysical assay development. As a startup company, this is a great opportunity to collaboratively build and contribute to the drugging strategy. The ideal candidate will have a strong background in assay development, an in-depth understanding of biochemistry and biophysics, and experience with small molecule drug discovery programs. The individual will play a central role in close coordination with internal scientists and collaboratively enable new projects for drug discovery.

Key Responsibilities:

  • Independently design, develop biochemical and biophysical assays for target enablement and hit finding
  • Characterize proteins, troubleshoot experiments, optimize assays suitable for SAR development
  • Conduct enzyme mechanism of action studies to guide screening and drug discovery approaches
  • Organize, manage, and analyze experimental data
  • Collaborate with diverse project teams internally to champion lead discovery and progression of small molecules
  • Analyze and present results at cross-functional team

Required Qualifications:

  • MS with 8-10 years or BS with 10-12 years or Ph.D. with 0-4 years of experience in small molecule drug discovery industry
  • Extensive experience in biochemical and binding assay development with a variety of readout formats (Fluorescence, FRET, LC-MS, FP, etc.)
  • Hands-on knowledge of biophysical methods such as SPR, DSF, SEC-MALS, ITC, etc. is required
  • Experience in assay optimization, steady state kinetics, mechanism of action studies, compound profiling, and screening
  • Experience in protein purification using AKTA systems
  • Excellent communication and collaborative skills to work on the project team with biologists, chemists, and metabolism scientists
  • Highly organized, self-motivated with the desire to succeed

For immediate consideration please share your CV complete with a full list of publications.


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